A Peripheral Blood Mononuclear Cell (PBMC) is a blood cell that has a round nucleus, such as a monocyte or a lymphocyte. These blood cells are critical components in the human immune system, and are therefore vital in fighting infections and adapting to intruding pathogens.
Cryopreserved PBMC reference samples: These can be both characterized or uncharacterized. With robust protocols for the cryopreservation of PBMCs, one can have more than 90% post-thaw viability. The resultant performance is easily comparable to that of fresh PBMCs. When frozen in accordance with the right serum-free protocols, they can avoid all the pitfalls of nonstandardized serum.
PBMCs can serve as positive or negative controls for T cell function measurement.
Properly cryopreserved peripheral blood mononuclear cells can have pre-defined reactivity for both CEF peptide pools and their individual peptides.